How do you administer a hespan?
HESPAN® is administered by intravenous infusion only. Total dosage and rate of infusion depend upon the amount of blood or plasma lost and the resultant hemoconcentration. The amount usually administered is 500 to 1000 mL.
When is hespan used?
Hespan is used to treat or prevent hypovolemia (decreased blood plasma volume, also called “shock”) that may occur as a result of serious injury, surgery, severe blood loss, burns, or other trauma. Hespan may also be used for purposes not listed in this medication guide.
Is hespan a blood product?
Indications and Usage for Hespan It is not a substitute for blood or plasma.
What type of solution is hetastarch?
HEXTEND (6% Hetastarch in Lactated Electrolyte Injection) is an artificial colloidal solution, pharmacologically classified as a plasma volume expander, and is intended to support oncotic pressure as well as provide electrolytes.
What type of solution is hespan?
HESPAN® (6% hetastarch in 0.9% sodium chloride injection) is a sterile, nonpyrogenic solution for intravenous administration. Hetastarch is a synthetic colloid derived from a waxy starch composed almost entirely of amylopectin.
What is dextran 40 used for?
LMD (dextran 40) is indicated for use in the adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma.
Is hetastarch hypotonic or hypertonic?
Hypertonic saline solution-hetastarch for fluid resuscitation in experimental septic shock.
Is hetastarch still used?
HES is used for volume expansion in the critically ill and for fluid resuscitation in trauma; however, HES appears to increase mortality and kidney injury in the critically ill and is no longer recommended by the United States Food and Drug Administration and European Medicines Agency.
Is hespan the same as Hetastarch?
What is the difference between dextran 40 and 70?
Dextrans have high water-binding capacity; for example, 1 g of dextran 40 retains 30 mL of water, while 1 g dextran 70 retains 20–25 mL of water. Dextran is mostly eliminated by the kidneys and should be avoided in patients with impaired renal function.
How do you give dextran 40?
Dextran 40 is a sterile, nonpyrogenic preparation of low molecular weight dextran (average mol. wt. 40,000) in 5% Dextrose Injection or 0.9% Sodium Chloride Injection. It is administered by intravenous infusion.
Does Epogen increase hemoglobin?
EPOGEN® increases Hb levels and decreases the need for blood transfusions. EPOGEN® should not be used in place of emergency red blood cell transfusions to treat anemia.
Is hetastarch isotonic?
A synthetic, nonionic hydroxyethyl derivative of starch used as a plasma expander when prepared in an isotonic solution. Upon intravenous administration, hydroxyethyl starch colloid increases blood volume and thus improves circulation.
How do you give hetastarch?
Hetastarch is given in boluses of 5–10 ml/kg over 5–10 minutes for hypovolaemia, or given as a continuous rate infusion (CRI) of 10–20 ml/kg/day. Like any colloid, Hetastarch can overexpand blood volume if given too rapidly or in large volumes, and is contraindicated in heart failure.
What are the results of Hespan infusion?
Intravenous infusion of Hespan® results in expansion of plasma volume. Hespan® results in expansion of plasma volume that decreases over the succeeding 24 to 36 hours. The degree of plasma volume expansion and improvement in hemodynamic state depend upon the patient’s intravascular status.
How do you administer Hespan in centrifuge?
250 to 700 mL of Hespan® (6% hetastarch in 0.9% sodium chloride injection) with citrate anticoagulant is administered by aseptic addition to the input line of the centrifugation apparatus at a ratio of 1:8 to 1:13 to venous whole blood.
What is the plasma volume produced by Hespan®?
The plasma volume expansion produced by Hespan® approximates that of 5% Albumin (Human). Intravenous infusion of Hespan® results in expansion of plasma volume. Hespan® results in expansion of plasma volume that decreases over the succeeding 24 to 36 hours.
What is a Hespan used for?
HESPAN ® is indicated in the treatment of hypovolemia when plasma volume expansion is desired. It is not a substitute for blood or plasma. Not made with latex, PVC or DEHP.