Which of the following adverse effects have been reported with Ethyol treatment?
Common side effects may include:
- nausea, vomiting;
- flushing (warmth, redness, or tingly feeling);
- fever, chills, general ill feeling;
- dizziness, drowsiness;
- hiccups, sneezing;
- blurred vision, double vision; or.
- pain, itching, redness, bruising, or swelling around the IV needle.
How is amifostine administered?
Amifostine is given by intravenous (into a vein) infusion. The treatment is given before radiation or chemotherapy starts. Patients are given the infusion while lying down and their blood pressure is monitored frequently.
What class of drug is amifostine?
OrganothiophosphateAmifostine / ClassificationOrganothiophosphates or organophosphorothioates are a subclass of organophosphorus compounds. Many are used as pesticides, some have medical applications, and some are used as oil additives. They generally have the chemical formula (RO)₃PS, [(RO)₂PO]⁻, R(RO)₂PS, etc. Wikipedia
How much does amifostine cost?
Average cost for amifostine was $4421 compared with $2709 for controls (difference $1711). For every 100 patients treated, 8 adverse events were avoided with an incremental cost-effectiveness ratio of $21,388 per adverse event avoided.
When should I take amifostine?
Amifostine is used protect the kidneys from harmful effects of the chemotherapy drug cisplatin in patients that receive this medication for the treatment of ovarian cancer. Amifostine is also used to decrease dryness in the mouth caused by radiation treatment after surgery for head and neck cancer.
Is leucovorin folic acid?
Leucovorin is in a class of medications called folic acid analogs. It works by protecting healthy cells from the effects of methotrexate or similar medications while allowing methotrexate to enter and kill cancer cells.
How will I feel after cyclophosphamide?
Cyclophosphamide often causes nausea, vomiting, and loss of appetite. However, it is very important that you continue to use the medicine even if you begin to feel ill. Do not stop taking this medicine without first checking with your doctor. Ask your doctor for ways to lessen these effects.
How long can I take cyclophosphamide for?
General. Cyclophosphamide is typically given in divided doses over a period of 2–5 days. It’s sometimes given two times per week or every 7–10 days. Your doctor will decide a dosing schedule that’s right for you.
Is amikacin safe in liver disease?
Amikacin as well as other aminoglycosides are not mentioned in large case series of drug induced liver disease and acute liver failure; thus, hepatic injury due to amikacin is very rare if it occurs at all. Likelihood score: E (unlikely cause of clinically apparent liver injury).
What is Ethyol?
Ethyol 1 DESCRIPTION. Amifostine is a white crystalline powder which is freely soluble in water. 2 INDICATIONS. ETHYOL (amifostine) is indicated to reduce the cumulative renal toxicity associated… 3 DOSAGE AND ADMINISTRATION. The recommended starting dose of ETHYOL is 910 mg/m 2 administered once… 4 SIDE EFFECTS. In the randomized study…
What are the side effects of Ethyol?
Other effects, which have been described during or following ETHYOL infusion are flushing/feeling of warmth, chills/feeling of coldness, malaise, pyrexia, rash, dizziness, somnolence, hiccups, diarrhea, sneezing, diplopia and blurred vision.
What is the recommended dose of Ethyol?
The recommended dose of ETHYOL is 200 mg/m2administered once daily as a 3-minute i.v. infusion, starting 15-30 minutes prior to standard fraction radiation therapy (1.8-2.0 Gy). Patients should be adequately hydrated prior to ETHYOL infusion.
What is Ethyol used for in cancer treatment?
Indications and Usage for Ethyol. Ethyol is indicated to reduce the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer, where the radiation port includes a substantial portion of the parotid glands (see Clinical Studies).