What is scaffolding in stents?
Most commercially available drug-eluting intracoronary stents (DES) consist of a metallic scaffold, a polymer coating (which may be durable or bioresorbable), and an antirestenotic drug that is mixed within the polymer and released over a period of weeks to months after implantation (table 1).
What are bioabsorbable stents how will they benefit patients?
In medicine, a stent is any device which is inserted into a blood vessel or other internal duct to expand it to prevent or alleviate a blockage. Traditionally, such devices are fabricated from metal mesh and remain in the body permanently or until removed through further surgical intervention.
What are bioabsorbable stents made of?
Most bioresorbable stents are made of polylactic acid, a naturally dissolvable material that is used in medical implants such as dissolving sutures.
What is the difference between shunt and stent?
A stent is different from a shunt. A shunt is a tube that connects two previously unconnected parts of the body to allow fluid to flow between them. Stents and shunts can be made of similar materials but perform two different tasks….
|3D rendering of a stent in a coronary artery
Are bioresorbable scaffold systems the future of stent technology?
Bioresorbable scaffold systems have the added benefit of completely degrading, which allows for recovery of vessel vasoreactivity and endothelial function. 1 For these reasons, bioresorbable scaffold systems represent a crucial next step in stent technology development.
Are resorbable scaffold stents safe?
Clinical research has shown that resorbable scaffolds, or naturally dissolving stents, offer comparable efficacy and safety profile to drug-eluting stents. Specifically, the Magmaris resorbable magnesium scaffold has reported a favorable safety profile with low target lesion failure and scaffold thrombosis rates.
What is the best scaffold material for a heart stent?
While polymer-based scaffolds had a strong presence at first, they have meanwhile lost some appeal due to safety concerns and focus is now shifted more towards metallic magnesium-based scaffolds. Metal stent candidates are iron, magnesium, zinc and their alloys.
Do bioabsorbable stents reduce thrombosis?
The Current Literature on Bioabsorbable Stents: a Review The ABSORB BVS, the most widely circulated stent of its class, was promised to decrease rates of stent thrombosis and target vessel revascularization.