What is meant by nucleic acid metabolism?
Nucleic acid metabolism is the process by which nucleic acids (DNA and RNA) are synthesized and degraded. Nucleic acids are the polymers of nucleotides. Nucleotide synthesis is an anabolic mechanism generally involving the chemical reaction of phosphate, pentose sugar, and a nitrogenous base.
What is nucleic acid PPT?
Kinds of Nucleic Acids DNA( deoxyribonucleic acid) –found only inside the nucleus of the cell. Contains the organism’s genetic information, including instructions for how to make proteins. RNA( ribonucleic acid) – found both inside and outside of the nucleus. Directs the building of proteins.
Why is nucleic acid metabolism important?
Nucleic acid metabolism generates and hydrolyzes DNA and RNA molecules and their components in the cell, in the processes of DNA replication, repair, recombination and turnover of DNA, transcription of RNA on DNA, and purine and pyrimidine synthesis and breakdown .
What is the process of nucleotide metabolism?
Nucleotide metabolism involves three amino acid donator reactions, serine to glycine reaction for methyl donation, aspartate to fumarate reaction for amine donation, and glutamine to glutamate reaction for amine donation (Fig. 5.6).
What organelle is responsible for nucleic acid metabolism?
Lysosomes: Lysosomes are membrane-bound organelles that contain digestive enzymes that break down proteins, lipids, carbohydrates, and nucleic acids.
What is the end product of nucleic acid metabolism?
Uric acid is a waste product that results from the breakdown of purine, a nucleic acid. Uric acid is made in the liver and excreted by the kidneys. If the liver produces too much uric acid or the kidneys excrete too little, the patient will have too much uric acid in the blood.
What are the classification of nucleic acids?
Nucleic acids are classified primarily as ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). Polymers made from sugars are either RNA or DNA depending on whether it is ribose sugar or the ribose derivative deoxyribose sugar.
What are the properties of nucleic acid?
Nucleic acids are long chainlike molecules composed of a series of nearly identical building blocks called nucleotides. Each nucleotide consists of a nitrogen-containing aromatic base attached to a pentose (five-carbon) sugar, which is in turn attached to a phosphate group.
How are nucleotide metabolism regulated?
The processes are regulated at the transcription level by a set of master transcription factors but also at the enzyme level by allosteric regulation and feedback inhibition. Here we review the cellular demands of nucleotide biosynthesis, their metabolic pathways and mechanisms of regulation during the cell cycle.
What is the role of nucleic acid?
Nucleic Acids Nucleic acids are large biomolecules that play essential roles in all cells and viruses. A major function of nucleic acids involves the storage and expression of genomic information. Deoxyribonucleic acid, or DNA, encodes the information cells need to make proteins.
What are the functions of nucleotides in cellular metabolism?
Nucleotides have a central role in the physiology of organisms as building blocks of nucleic acids, storage of chemical energy, carriers of activated metabolites for biosynthesis, structural moieties of coenzymes, and metabolic regulators.
What is the main function of a nucleic acid?
Nucleic Acids A major function of nucleic acids involves the storage and expression of genomic information. Deoxyribonucleic acid, or DNA, encodes the information cells need to make proteins.
What is the main function of nucleic acid?
What is the most important function of nucleic acids?
By far the most important function of nucleic acids for living things is their role as carriers of information.
What are the 3 main functions of nucleic acids?
The three main functions of nucleic acids are gene expression and regulation of cellular activities, storage and transmission of genetic information.
What are nucleic acids functions?
Nucleic acids are large biomolecules that play essential roles in all cells and viruses. A major function of nucleic acids involves the storage and expression of genomic information. Deoxyribonucleic acid, or DNA, encodes the information cells need to make proteins.
What are characteristics of nucleic acids?
Nucleic Acids: Structure, Function, Types & Examples These units are called nucleotides. All nucleotides in turn include three distinct chemical portions: a pentose sugar, a phosphate group and a nitrogenous base.
What is classification of nucleic acid?
What is the main role of nucleic acid?
What is nucleic acid metabolism?
UNIT- IV Nucleic Acid Metabolism ANKUSH GOYAL ASSISTANT PROFESSOR MAHARAJAAGRASEN SCHOOL OF PHARMACY MAHARAJAAGRASEN UNIVERSITY, BADDI (H.P.) 2. Nucleic Acids (Polymer of Nucleotides) Nucleic acids are the polymers of nucleotides (polynucleotides) held by 3’ and 5’ phosphate bridges.
What is the primary structure of a nucleic acid?
• The primary structureof a nucleic acid is the nucleotide sequence • The nucleotides in nucleic acids are joined by phosphodiester bonds • The 3’-OH group of the sugar in one nucleotide forms an ester bond to the phosphate group on the 5’-carbon of the sugar of the next nucleotide Friday, November 24, 9 2017 NUCLEIC ACID METABOLISM : ABN 320
How did the name of nucleic acid come about?
2. HISTORIC RESUME Friedrich Miescher in 1869 • Isolated what he called nuclein from the nuclei of pus cells • Nuclein was shown to have acidic properties, hence it became called nucleic acid 3. NUCLEIC ACID • Nucleic acid are polymers that consist of nucleotide residues.
What are the types of nucleic acids found in the nucleus?
TYPES OF NUCLEIC ACID • Deoxyribonucleic acid (DNA) • Ribonucleic acid (RNA) 5. The distribution of nucleic acids in the eukaryotic cell • DNA is found in the nucleus with small amounts in mitochondria and chloroplasts • RNA is found throughout the cell